exRNAdisease

Entry Detail

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General Information

Database ID: exR0755327 RNA Name: ABRAXAS1 RNA Type: mRNA Chromosome: chr4 Starnd: - Coordinate: Start Site(bp): 83459517 End Site(bp): 83523348 External Links: ENSG00000163322

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ARF6 chr14 49893082 49897054 + ARHGAP11B chr15 30624494 30649529 + CEBPZ chr2 37201612 37231596 - CHD8 chr14 21385194 21456126 - CSDE1 chr1 114716913 114758676 - DYRK1A chr21 37365573 37526358 + DYRK3 chr1 206635536 206684419 + ETF1 chr5 138506095 138543236 - FADS2 chr11 61792980 61867354 + HELQ chr4 83407343 83455855 - KDM3A chr2 86440647 86492716 + PLEKHA5 chr12 19129752 19376400 + POU6F1 chr12 51186936 51217708 - PRDM4 chr12 107732871 107761272 - REXO4 chr9 133406059 133418096 - STK17B chr2 196133583 196176503 - TOMM20 chr1 235109341 235128837 - XRCC6 chr22 41621119 41664048 + miRNA targets: NA circRNA targets: NA lncRNA targets: NA Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.