exRNAdisease

Entry Detail

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General Information

Database ID: exR0755328 RNA Name: ABRAXAS2 RNA Type: mRNA Chromosome: chr10 Starnd: + Coordinate: Start Site(bp): 124801819 End Site(bp): 124836667 External Links: ENSG00000165660

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AIF1L chr9 131096476 131123152 + ATP2A2 chr12 110280756 110351093 + ATP5F1A chr18 46080248 46104334 - BEX3 chrX 103376395 103378164 + EDARADD chr1 236348257 236502915 + FAR2 chr12 29149103 29340980 + FNIP1 chr5 131641714 131797063 - FRAS1 chr4 78057323 78544269 + GNG4 chr1 235547685 235650754 - GSTP1 chr11 67583742 67586656 + ID2 chr2 8678845 8684461 + IRAK1 chrX 154010506 154019902 - KCNK5 chr6 39188971 39229475 - MSH6 chr2 47695530 47810101 + NAA10 chrX 153929225 153935080 - PLEKHA1 chr10 122374696 122442602 + POGLUT1 chr3 119468963 119494708 + RHOB chr2 20447074 20449440 + RND1 chr12 48857145 48865870 - RPL18A chr19 17859910 17864153 + RPL7 chr8 73290242 73295789 - SF3B5 chr6 144094884 144095573 - SSRP1 chr11 57325986 57335892 - UQCRH chr1 46303698 46316776 + VEGFB chr11 64234538 64238793 + miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC079248.1 chr2 145872209 145931146 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.