exRNAdisease

Entry Detail

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General Information

Database ID: exR0755329 RNA Name: ABT1 RNA Type: mRNA Chromosome: chr6 Starnd: + Coordinate: Start Site(bp): 26596953 End Site(bp): 26600739 External Links: ENSG00000146109

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand HSP90AB1 chr6 44246166 44253888 + RPS20 chr8 56067295 56074581 - SLC37A4 chr11 119024114 119030906 - PAFAH1B2 chr11 117144284 117176894 + RNASEH2C chr11 65714005 65720818 - CLTA chr9 36190856 36304781 + USF1 chr1 161039251 161045977 - POR chr7 75899200 75986855 + ENO1 chr1 8861000 8879190 - RPL22L1 chr3 170864875 170870208 - RAN chr12 130872037 130877678 + GSTP1 chr11 67583742 67586656 + PDLIM1 chr10 95237572 95291012 - MPDU1 chr17 7583529 7592789 + HSPD1 chr2 197486584 197516737 - THOC5 chr22 29505879 29555216 - PAK1IP1 chr6 10694972 10709782 + CHCHD10 chr22 23765834 23768443 - DHRS4L2 chr14 23969874 24006408 + GFOD1 chr6 13357830 13487662 - DNAJC14 chr12 55820960 55830824 - NFE2L1 chr17 48048329 48061545 + SFRP1 chr8 41261962 41309473 - B2M chr15 44711487 44718877 + BABAM1 chr19 17267376 17281249 + GTPBP1 chr22 38705742 38738299 + IL4R chr16 27313668 27364778 + HLA-DRA chr6 32439878 32445046 + MCFD2 chr2 46901870 46941855 - EEF1A1 chr6 73515750 73523797 - miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-873-5p chr9 28888925 28888945 - circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC008969.1 chr19 58002061 58011232 + AC020663.1 chr16 4730115 4752565 - MALAT1 chr11 65497688 65506516 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.