Entry Detail


General Information

Database ID:exR0755333
RNA Name:AC003002.3
RNA Type:mRNA
Chromosome:chr19
Starnd:+
Coordinate:
Start Site(bp):57389884End Site(bp):57419994
External Links:ENSG00000269533



Disease Information

Disease Name:Glioblastoma Multiforme
Disease Category:Cancers
MeSH ID:D005909
Type:Neoplasms/Neoplasms, Glandular and Epithelial
Alias:Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell



Expression Detail

GEO ID:GSE106804
Description:Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles
Experimental Design:Cancer vs Control
Case Disease Type:Glioblastoma Multiforme
Case Disease SubType:NA
Case Sample:Glioblastoma Multiforme
Control Sample:Healthy
Number of Case:13
Number of Control:6
Number of Samples:19





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC020915.5
chr19
58228914
58315183
+
ERVK3-1
chr19
58305319
58315663
+
LYN
chr8
55879835
56014169
+
MCM3AP
chr21
46235133
46286297
-
MTCH1
chr6
36968141
36986298
-
PRKCE
chr2
45651345
46187990
+
RPL4
chr15
66498015
66524532
-
VHL
chr3
10141008
10152220
+
ZNF17
chr19
57411163
57421939
+
ZNF773
chr19
57499915
57518404
+
ZNF814
chr19
57848731
57889074
-
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC020915.1
chr19
58278966
58315197
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:29330365
Title:Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles.
Author:Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL.
Journal:Nat Commun. 2018 Jan 12;9(1):175.
Description:Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.