exRNAdisease

Entry Detail

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General Information

Database ID: exR0755336 RNA Name: AC010422.3 RNA Type: mRNA Chromosome: chr19 Starnd: - Coordinate: Start Site(bp): 12643831 End Site(bp): 12648397 External Links: ENSG00000269242

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AC011462.1 chr19 41350853 41425001 + AGFG1 chr2 227472152 227561214 + ACOT7 chr1 6264269 6394391 - ACVR1B chr12 51951699 51997078 + ADD1 chr4 2843857 2930076 + ADA2 chr22 17178790 17258235 - AARD chr8 116938207 116944487 + AC004922.1 chr7 99325879 99394653 + AJAP1 chr1 4654609 4792534 + AL358113.1 chr9 69035747 69255187 + AGPAT5 chr8 6708642 6761503 + AATF chr17 36948954 37056871 + ACAA2 chr18 49782164 49813953 - ACTB chr7 5527148 5563784 - ADIPOR2 chr12 1688574 1788674 + AC020915.5 chr19 58228914 58315183 + ADRA1D chr20 4220630 4249287 - ADRA2C chr4 3766348 3768526 + AC020922.1 chr19 55352301 55359516 - ACSF3 chr16 89088375 89164121 + AC131160.1 chr3 183815568 183884889 - ADRA2A chr10 111077029 111080907 + ABHD17A chr19 1876810 1885547 - AKT2 chr19 40230317 40285536 - AEBP2 chr12 19404045 19720801 + AASS chr7 122073549 122144255 - AL451007.3 chr1 244729898 244730962 - ADCY1 chr7 45574140 45723116 + AC008982.1 chr19 38817471 38840178 - ADORA1 chr1 203090654 203167405 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-3960 chr9 127785879 127785898 + hsa-miR-7704 chr2 176188843 176188861 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC007216.1 chr16 11976851 11977850 - AC027097.2 chr18 57639455 57738603 + AP001266.1 chr11 65795946 65797219 - AC133550.2 chr16 28830612 28837200 - AL121897.1 chr20 32275117 32277510 - TAPT1-AS1 chr4 16226685 16320140 + AL031005.1 chr1 21266082 21267251 + AC239799.1 chr1 146235806 146237807 + ADGRA1-AS1 chr10 133083073 133088491 - AC005332.5 chr17 68133201 68135935 + AC026362.1 chr12 122975320 122982907 + BAALC-AS1 chr8 103153394 103298772 - MAGI2-AS3 chr7 79452877 79471208 + PVT1 chr8 127794526 128187101 + AL121992.1 chr1 15586136 15603626 - SNHG6 chr8 66921684 66926398 - AL355075.4 chr14 20343048 20343685 - AC079807.1 chr2 47905678 47907810 + KMT2E-AS1 chr7 105013425 105014321 - AC138761.1 chr17 22266395 22288301 + AC009133.5 chr16 29808679 29812227 + AC027097.1 chr18 57630302 57669296 + AC008738.5 chr19 33301279 33301940 + CCDC144NL-AS1 chr17 20868433 21002276 + AP000547.3 chr22 16601911 16615111 + AL354920.1 chr9 83707594 83713378 + AL121987.1 chr1 160062461 160080769 + AL022311.1 chr22 37876148 37895563 + AC020928.2 chr19 36773712 36775908 - AP001160.2 chr11 62771120 62771606 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.