exRNAdisease

Entry Detail

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General Information

Database ID: exR0755337 RNA Name: AC011511.1 RNA Type: mRNA Chromosome: chr19 Starnd: - Coordinate: Start Site(bp): 10305427 End Site(bp): 10316009 External Links: ENSG00000167807

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AC011511.4 chr19 10315471 10320678 - B2M chr15 44711487 44718877 + C19orf81 chr19 50649445 50659310 + CLASP2 chr3 33496245 33718356 - CMAS chr12 22046218 22065674 + EXOSC5 chr19 41386374 41397359 - FDX2 chr19 10310045 10316015 - GLO1 chr6 38675925 38703145 - GNAI2 chr3 50226292 50259362 + IRF2BP1 chr19 45883608 45886141 - KNOP1 chr16 19701937 19718235 - LITAF chr16 11547722 11636381 - MT-CO2 chrMT 7586 8269 + NACC1 chr19 13116862 13141147 + PHB2 chr12 6965327 6970753 - PPIF chr10 79347469 79355334 + RPLP0 chr12 120196699 120201235 - RPS19 chr19 41860255 41872925 + RPUSD4 chr11 126202096 126211692 - SIPA1L3 chr19 37907208 38208369 + SPRYD3 chr12 53064316 53079404 - TCF12 chr15 56918623 57299281 + TPRA1 chr3 127571232 127598267 - UBALD2 chr17 76265348 76271298 + ZGLP1 chr19 10304803 10309880 - miRNA targets: NA circRNA targets: NA lncRNA targets: NA Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.