exRNAdisease

Entry Detail

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General Information

Database ID: exR0755338 RNA Name: AC013394.1 RNA Type: mRNA Chromosome: chr15 Starnd: + Coordinate: Start Site(bp): 92883413 End Site(bp): 92949230 External Links: ENSG00000279765

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand CHCHD1 chr10 73782047 73783652 + CHD2 chr15 92900189 93027996 + CSTF2T chr10 51695486 51699595 - ERLIN2 chr8 37736601 37758422 + EXOC5 chr14 57200507 57268905 - FADS2 chr11 61792980 61867354 + FAM120B chr6 170290703 170407065 + FASTKD1 chr2 169528508 169573875 - HNRNPR chr1 23303771 23344336 - ITM2C chr2 230864639 230879248 + LSR chr19 35248330 35267964 + MBOAT2 chr2 8852690 9003709 - MDK chr11 46380756 46383837 + MON2 chr12 62466817 62600476 + MT-CO3 chrMT 9207 9990 + NAPRT chr8 143574785 143578649 - NCL chr2 231453531 231483641 - PCNT chr21 46324141 46445769 + PSAT1 chr9 78297125 78330093 + RPL4 chr15 66498015 66524532 - RPRD1A chr18 35984387 36067576 - SEC24D chr4 118722823 118838683 - SH3PXD2B chr5 172325000 172454525 - SLK chr10 103967140 104029233 + SRSF1 chr17 58000919 58007346 - TNRC6C chr17 77959240 78108835 + TUBB chr6 30720352 30725426 + ZPR1 chr11 116773799 116788039 - miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand GAS5 chr1 173858559 173868882 - LINC01578 chr15 92819540 92899701 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.