exRNAdisease

Entry Detail

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General Information

Database ID: exR0755342 RNA Name: AC079447.1 RNA Type: mRNA Chromosome: chr2 Starnd: + Coordinate: Start Site(bp): 99141485 End Site(bp): 99322741 External Links: ENSG00000241962

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AC092587.1 chr2 99154998 99195298 + ACACA chr17 37084992 37406836 - C2orf15 chr2 99141485 99151487 + CCND2 chr12 4273762 4305353 + COX4I1 chr16 85798633 85807068 + DBI chr2 119366921 119372560 + DCTN1 chr2 74361154 74392087 - EIF3E chr8 108201216 108435333 - GRAMD1A chr19 34994784 35026471 + GRB2 chr17 75318076 75405709 - HDAC9 chr7 18086949 19002416 + HSP90AB1 chr6 44246166 44253888 + KIF2C chr1 44739818 44767767 + KIF3C chr2 25926598 25982749 - LIPT1 chr2 99154955 99163157 + MRPL30 chr2 99181152 99199561 + PDIA6 chr2 10783391 10837977 - STOML2 chr9 35099776 35103195 - TM9SF4 chr20 32109714 32167258 + miRNA targets: NA circRNA targets: NA lncRNA targets: NA Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.