exRNAdisease

Entry Detail

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General Information

Database ID: exR0755343 RNA Name: AC091959.3 RNA Type: mRNA Chromosome: chr5 Starnd: + Coordinate: Start Site(bp): 146203550 End Site(bp): 146339251 External Links: ENSG00000275740

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand CLDN15 chr7 101232092 101238820 - ERP29 chr12 112013348 112023449 + RPL13 chr16 89560657 89566828 + CXCR5 chr11 118883892 118897787 + UBAP2L chr1 154220179 154271510 + ARHGAP19 chr10 97222173 97292673 - PIGS chr17 28553383 28571794 - NUCKS1 chr1 205712822 205750182 - NIPSNAP1 chr22 29554808 29581327 - GDE1 chr16 19501693 19522123 - PICALM chr11 85957175 86069882 - AC008763.3 chr19 7678501 7682854 + TUBB chr6 30720352 30725426 + IGSF8 chr1 160091340 160098943 - HSPA8 chr11 123057489 123063230 - RBM27 chr5 146203605 146289223 + CERS1 chr19 18868545 18896727 - UBL4A chrX 154483717 154486615 - SERGEF chr11 17788048 18013047 - THOC5 chr22 29505879 29555216 - ANP32E chr1 150218417 150236156 - RIPOR1 chr16 67518418 67546788 + LMBRD1 chr6 69672757 69867236 - TPT1 chr13 45333471 45341370 - HRAS chr11 532242 537287 - TICRR chr15 89575469 89631056 + IDH3B chr20 2658395 2664219 - TRAPPC5 chr19 7680833 7687703 + PGAM1 chr10 97426191 97433444 + MARCKSL1 chr1 32333839 32336233 - miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC055860.1 chr11 18000542 18022931 - HOTAIRM1 chr7 27095647 27100265 + NNT-AS1 chr5 43571594 43603230 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.