exRNAdisease

Entry Detail

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General Information

Database ID: exR0755345 RNA Name: AC118553.2 RNA Type: mRNA Chromosome: chr1 Starnd: + Coordinate: Start Site(bp): 99970011 End Site(bp): 100083321 External Links: ENSG00000283761

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand CFL1 chr11 65823022 65862026 - BAK1 chr6 33572547 33580293 - SLC35A3 chr1 99969351 100035634 + TMEM69 chr1 45688181 45694436 + MBNL1 chr3 152243828 152465780 + VDAC2 chr10 75210154 75231448 + SRP72 chr4 56467617 56503681 + YEATS2 chr3 183697797 183812624 + ADD1 chr4 2843857 2930076 + PFDN5 chr12 53295291 53299450 + UGP2 chr2 63840940 63891562 + MRFAP1 chr4 6640091 6642745 + GOT2 chr16 58707131 58734342 - USP34 chr2 61187463 61471087 - TJP2 chr9 69121264 69274615 + SPRYD7 chr13 49912702 49936490 - CKS2 chr9 89311195 89316703 + EEF1G chr11 62559596 62574086 - COPE chr19 18899514 18919387 - HIF1AN chr10 100529072 100559998 + IGFBP2 chr2 216632828 216664436 + PODXL chr7 131500262 131558217 - RALBP1 chr18 9475009 9538114 + SNAP23 chr15 42491233 42545356 + BAZ1B chr7 73440406 73522293 - FADS1 chr11 61799627 61829318 - TMEM256 chr17 7402975 7404097 - SLC12A8 chr3 125082636 125212864 - MFSD14A chr1 100038095 100083377 + IMP3 chr15 75639085 75648706 - miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AP001496.2 chr18 5232876 5238526 - EPB41L4A-AS1 chr5 112160526 112164818 + SNHG12 chr1 28578538 28583132 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.