exRNAdisease

Entry Detail

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General Information

Database ID: exR0755346 RNA Name: AC138894.1 RNA Type: mRNA Chromosome: chr16 Starnd: - Coordinate: Start Site(bp): 28456371 End Site(bp): 28492098 External Links: ENSG00000261832

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand SAT1 chrX 23783173 23786226 + METTL3 chr14 21498133 21511342 - NPIPA1 chr16 14922802 14952060 + CCDC51 chr3 48432164 48440456 - AC138969.1 chr16 16317444 16350590 + ZSWIM8 chr10 73785582 73801797 + NPIPA8 chr16 18317942 18336736 - CPSF1 chr8 144393229 144409335 - USP48 chr1 21678298 21783606 - NPIPB6 chr16 28342555 28363508 - KIAA0556 chr16 27550133 27780369 + NPIPB12 chr16 29483642 29505999 - ADD2 chr2 70607618 70768225 - ACTB chr7 5527148 5563784 - NPIPB5 chr16 22479121 22536521 + KDM5A chr12 280057 389320 - MROH1 chr8 144148016 144261940 + RPL36 chr19 5674947 5691875 + SUPT5H chr19 39436156 39476670 + HNRNPA1 chr12 54280193 54287088 + HNRNPA1P48 chr16 51553436 51647132 + TUBB2B chr6 3224277 3231730 - AP3D1 chr19 2100988 2164468 - FREM2 chr13 38687077 38887131 + MAP3K5 chr6 136557046 136792477 - TUBA1B chr12 49127782 49131397 - MMS19 chr10 97458324 97498794 - AGPAT3 chr21 43865223 43987592 + MED24 chr17 40019097 40061215 - TBC1D15 chr12 71839707 71927248 + miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand MALAT1 chr11 65497688 65506516 + RRN3P2 chr16 29074976 29116718 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.