exRNAdisease

Entry Detail

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General Information

Database ID: exR0755347 RNA Name: AC138969.1 RNA Type: mRNA Chromosome: chr16 Starnd: + Coordinate: Start Site(bp): 16317444 End Site(bp): 16350590 External Links: ENSG00000183889

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand DCAF1 chr3 51395867 51500002 - PILRB chr7 100352176 100367733 + CABYR chr18 24138956 24161603 + TKT chr3 53224712 53256052 - NPIPA8 chr16 18317942 18336736 - MAN1A1 chr6 119177205 119349761 - FBXO21 chr12 117141988 117190531 - PKD1 chr16 2088708 2135898 - SEH1L chr18 12947133 12987536 + NPIPB8 chr16 28637654 28658682 + C19orf48 chr19 50797704 50804929 - RPN2 chr20 37178410 37241619 + HDGFL2 chr19 4472297 4502208 + FTL chr19 48965309 48966879 + RCN2 chr15 76931738 76954393 + NPIPB11 chr16 29381354 29404029 - CNTROB chr17 7932101 7949920 + NPIPB3 chr16 21402237 21448567 - TCTN1 chr12 110614027 110649430 + TICRR chr15 89575469 89631056 + LMNB2 chr19 2427638 2456959 - GPRC5B chr16 19856691 19886167 - HOXD9 chr2 176122719 176124937 + RRM1 chr11 4094707 4138932 + AKR7A2 chr1 19303965 19312146 - CSNK1E chr22 38290691 38318084 - DYNC1H1 chr14 101964573 102056443 + PURA chr5 140107777 140125619 + NPIPA2 chr16 14748066 14765413 + AMFR chr16 56361452 56425545 - miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AL031005.1 chr1 21266082 21267251 + SNHG12 chr1 28578538 28583132 - SNHG16 chr17 76557764 76565348 + STAG3L5P-PVRIG2P-PILRB chr7 100336104 100367831 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.