exRNAdisease

Entry Detail

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General Information

Database ID: exR0755348 RNA Name: ACAA2 RNA Type: mRNA Chromosome: chr18 Starnd: - Coordinate: Start Site(bp): 49782164 End Site(bp): 49813953 External Links: ENSG00000167315

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand DCAF5 chr14 69050881 69153150 - PSMA6 chr14 35278633 35317493 + RPL13 chr16 89560657 89566828 + GSPT1 chr16 11868128 11916082 - GABARAP chr17 7240008 7242449 - DNAJC1 chr10 21756548 22003769 - LRRN1 chr3 3799431 3849834 + SRSF7 chr2 38743599 38751494 - MAPKAP1 chr9 125437393 125707234 - CLDND1 chr3 98497912 98523066 - AC120057.2 chr17 7240427 7244635 - KDM5C chrX 53191321 53225422 - RAB6A chr11 73675638 73761137 - EXOC6B chr2 72175984 72826041 - CDC20 chr1 43358981 43363203 + SF3B6 chr2 24067586 24076373 - UBL5 chr19 9827892 9830115 + MTRNR2L12 chr3 96617188 96618236 - HACD4 chr9 20999509 21031640 - RAN chr12 130872037 130877678 + RAD17 chr5 69369293 69414801 + RPS6 chr9 19375715 19380236 - REEP5 chr5 112876385 112922289 - LRRFIP1 chr2 237627587 237813682 + VASP chr19 45506579 45526983 + CAPN1 chr11 65180566 65212006 + CKAP5 chr11 46743048 46846308 - NTS chr12 85874295 85882992 + ERN1 chr17 64039142 64130819 - PRDX6 chr1 173477330 173488815 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-492 chr12 94834427 94834449 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC026362.1 chr12 122975320 122982907 + AD000090.1 chr19 35557956 35581954 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.