exRNAdisease

Entry Detail

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General Information

Database ID: exR0755352 RNA Name: ACADM RNA Type: mRNA Chromosome: chr1 Starnd: + Coordinate: Start Site(bp): 75724347 End Site(bp): 75787575 External Links: ENSG00000117054

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand DBN1 chr5 177456608 177474401 - HMGA1 chr6 34236873 34246231 + ARID5A chr2 96536743 96552634 + RPN2 chr20 37178410 37241619 + HACD3 chr15 65530418 65578349 + ITGB3BP chr1 63440770 63593721 - HYOU1 chr11 119044188 119057227 - SLC35G1 chr10 93893973 93956062 + RBMXL1 chr1 88979456 88992960 - DTX4 chr11 59171430 59208588 + FOXN2 chr2 48314637 48379295 + PNN chr14 39175183 39183220 + BUB1B chr15 40161023 40221136 + DDX39B chr6 31530219 31542448 - GDI2 chr10 5765223 5842132 - FTL chr19 48965309 48966879 + PKM chr15 72199029 72231822 - SRRM1 chr1 24631716 24673281 + EXOSC8 chr13 36998816 37009614 + DHX8 chr17 43483865 43610338 + TRPC4 chr13 37636636 37870425 - POLDIP3 chr22 42583721 42614962 - RPL30 chr8 98024851 98046469 - COA7 chr1 52684449 52698347 - DNMT3B chr20 32762385 32809356 + ATP6V1G2-DDX39B chr6 31530219 31546608 - RPS24 chr10 78033760 78056813 + NR1H2 chr19 50329653 50383388 + NCOA4 chr10 46005088 46030714 - XPO1 chr2 61477849 61538626 - miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC004812.2 chr12 120116907 120119000 + AC009948.2 chr2 178548884 178550681 + AC069287.1 chr11 112967 125927 - AL831711.1 chr1 161433444 161440996 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.