exRNAdisease

Entry Detail

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General Information

Database ID: exR0755353 RNA Name: ACADSB RNA Type: mRNA Chromosome: chr10 Starnd: + Coordinate: Start Site(bp): 123008979 End Site(bp): 123058290 External Links: ENSG00000196177

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand B2M chr15 44711487 44718877 + B4GAT1 chr11 66345374 66347629 - BUB3 chr10 123154402 123170467 + C11orf58 chr11 16613132 16758340 + CCND2 chr12 4273762 4305353 + COX18 chr4 73052362 73069755 - DDX24 chr14 94048287 94081212 - DHCR24 chr1 54849627 54887195 - EIF4E chr4 98871684 98930637 - HLA-B chr6 31269491 31357188 - MCFD2 chr2 46901870 46941855 - MICB chr6 31494881 31511124 + NCOR1 chr17 16029157 16218185 - NFATC3 chr16 68084751 68229259 + NOP53 chr19 47745546 47757058 + POGK chr1 166839447 166856344 + POLE3 chr9 113407235 113410675 - RFFL chr17 35005990 35089319 - TPT1 chr13 45333471 45341370 - VMP1 chr17 59707192 59842255 + YWHAE chr17 1344275 1400222 - YWHAQ chr2 9583967 9630997 - ZNF100 chr19 21722771 21767579 - miRNA targets: NA circRNA targets: NA lncRNA targets: NA Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.