exRNAdisease

Entry Detail

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General Information

Database ID: exR0755355 RNA Name: ACAP1 RNA Type: mRNA Chromosome: chr17 Starnd: + Coordinate: Start Site(bp): 7336529 End Site(bp): 7351477 External Links: ENSG00000072818

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand HLA-DRA chr6 32439878 32445046 + FOXH1 chr8 144473412 144475849 - ZNF449 chrX 135344796 135363413 + MIF chr22 23894383 23895227 + KDF1 chr1 26949562 26960468 - SQSTM1 chr5 179806398 179838078 + PFN1 chr17 4945652 4949061 - CD74 chr5 150400041 150412929 - RGS10 chr10 119499817 119542719 - TUBB chr6 30720352 30725426 + ISG15 chr1 1001138 1014540 + C20orf204 chr20 64034344 64039962 + AL133352.1 chr10 100505628 100529881 - DHX16 chr6 30653119 30673006 - AP002990.1 chr11 62559603 62591531 - UGCG chr9 111896814 111935369 + DNAJC30 chr7 73680918 73683453 - ACTG1 chr17 81509971 81523847 - VPS53 chr17 508668 721717 - HLA-DMA chr6 32948613 32969094 - CDC25B chr20 3786772 3806121 + RCC1 chr1 28505943 28539300 + YME1L1 chr10 27110112 27155266 - REEP3 chr10 63521401 63625128 + CD70 chr19 6583183 6604103 - ZNF593 chr1 26169908 26170873 + NSMF chr9 137447573 137459334 - EXOC3 chr5 443175 471937 + ZNF761 chr19 53445001 53458261 + APH1A chr1 150265399 150269580 - miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC139149.1 chr17 81514047 81527776 + LINC01184 chr5 127939152 128083172 - SNHG3 chr1 28505980 28510892 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.