exRNAdisease

Entry Detail

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General Information

Database ID: exR0755358 RNA Name: ACAT1 RNA Type: mRNA Chromosome: chr11 Starnd: + Coordinate: Start Site(bp): 108116695 End Site(bp): 108147603 External Links: ENSG00000075239

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ATP2A2 chr12 110280756 110351093 + MTRNR2L8 chr11 10507894 10509186 - TRIP10 chr19 6737925 6751530 + NPEPPS chr17 47522942 47623276 + DAPK1 chr9 87497228 87708634 + PSMB5 chr14 23016543 23035230 - CCDC102A chr16 57512181 57536571 - FZD3 chr8 28494205 28574267 + NCAM1 chr11 112961247 113278436 + PRDX4 chrX 23664262 23686397 + PSMD10 chrX 108084207 108091549 - PGK1 chrX 77910739 78129295 + HSP90AB1 chr6 44246166 44253888 + NPIPB2 chr16 11927259 11976643 - TXNRD1 chr12 104215779 104350307 + MRPL47 chr3 179588285 179604649 - AC010422.3 chr19 12643831 12648397 - GHITM chr10 84139509 84153568 + POU3F3 chr2 104853287 104858574 + RPS4X chrX 72255679 72277248 - DAP3 chr1 155687960 155739010 + EEF1A1 chr6 73515750 73523797 - GLI2 chr2 120735623 120992653 + IER3IP1 chr18 47152834 47176364 - RPLP1 chr15 69452814 69456205 + ACTG1 chr17 81509971 81523847 - IGFBP2 chr2 216632828 216664436 + NUP205 chr7 135557917 135648757 + ACTB chr7 5527148 5563784 - TXNDC16 chr14 52430596 52552522 - miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand MIR155HG chr21 25561909 25575168 + POLR2J4 chr7 43940895 44019175 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.