exRNAdisease

Entry Detail

---



General Information

Database ID: exR0755359 RNA Name: ACBD3 RNA Type: mRNA Chromosome: chr1 Starnd: - Coordinate: Start Site(bp): 226144679 End Site(bp): 226186741 External Links: ENSG00000182827

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand MTRNR2L12 chr3 96617188 96618236 - SLC16A2 chrX 74421493 74533917 + RPS24 chr10 78033760 78056813 + NUSAP1 chr15 41320794 41381050 + LRWD1 chr7 102464956 102473168 + S1PR4 chr19 3172346 3180332 + RSU1 chr10 16590611 16817463 - RPL15 chr3 23916545 23924374 + FOCAD chr9 20658309 20995955 + GPR176 chr15 39799008 39920266 - RAPGEF1 chr9 131576770 131740074 - UTP18 chr17 51260546 51297936 + LIMCH1 chr4 41359607 41700044 + ZNF224 chr19 44094339 44109886 + TTC39C chr18 23992773 24135610 + IGFBP5 chr2 216672105 216695549 - YTHDF1 chr20 63195429 63216139 - RGS10 chr10 119499817 119542719 - CFL1 chr11 65823022 65862026 - TPT1 chr13 45333471 45341370 - RASGRP2 chr11 64726911 64745456 - ACLY chr17 41866917 41930542 - UQCRQ chr5 132866630 132868847 + ID4 chr6 19837370 19842197 + CSNK1E chr22 38290691 38318084 - PUM1 chr1 30931506 31065991 - ZBTB33 chrX 120250752 120258398 + TSN chr2 121737103 121767853 + HK1 chr10 69269984 69401884 + DNPEP chr2 219373527 219400022 - miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC009404.1 chr2 117833937 117841658 + AC023908.2 chr15 39770559 39801333 - AL022311.1 chr22 37876148 37895563 + AL513314.2 chr1 222477252 222504622 - MIR663AHG chr20 26167817 26251546 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.