exRNAdisease

Entry Detail

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General Information

Database ID: exR0755360 RNA Name: ACBD4 RNA Type: mRNA Chromosome: chr17 Starnd: + Coordinate: Start Site(bp): 45132600 End Site(bp): 45144181 External Links: ENSG00000181513

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ANP32A chr15 68778535 68820897 - BSG chr19 571277 583493 + CCDC6 chr10 59788747 59906556 - CDON chr11 125955796 126063335 - DYNLL2 chr17 58083419 58095542 + EIF3C chr16 28688558 28735730 + ENO1 chr1 8861000 8879190 - GAPDH chr12 6534512 6538374 + GATAD1 chr7 92447482 92460075 + HPN chr19 35040506 35066571 + KAT7 chr17 49788681 49835026 + LIN28A chr1 26410817 26429728 + LRP4 chr11 46856717 46918642 - MAD2L2 chr1 11674480 11691650 - PDE4D chr5 58969038 60522120 - PDHB chr3 58427630 58433857 - PPP6R1 chr19 55229779 55259017 - SCAND1 chr20 35953617 35959472 - TMA16 chr4 163494442 163520539 + TPM3 chr1 154155304 154194648 - TPRN chr9 137191617 137204193 - TSR1 chr17 2322396 2336657 - TUBA1B chr12 49127782 49131397 - USP39 chr2 85602856 85649283 + VPS26C chr21 37223420 37267919 - miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC027290.2 chr12 122865335 122867021 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.