exRNAdisease

Entry Detail

---



General Information

Database ID: exR0755362 RNA Name: ACBD6 RNA Type: mRNA Chromosome: chr1 Starnd: - Coordinate: Start Site(bp): 180269653 End Site(bp): 180502954 External Links: ENSG00000230124

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand TMEM187 chrX 153972754 153983194 + SIGMAR1 chr9 34634722 34637809 - COPS7A chr12 6724014 6731875 + SPTLC3 chr20 13008972 13169103 + BLOC1S1 chr12 55716037 55720087 + TOB2 chr22 41433494 41446801 - ACAP3 chr1 1292390 1309609 - AC011455.2 chr19 38915404 38949855 - TUBA1A chr12 49184795 49189080 - GLTP chr12 109850945 109880541 - FBXO17 chr19 38941401 38975742 - CMTM4 chr16 66614750 66696707 - AC055811.2 chr17 17202649 17237185 - PHACTR4 chr1 28369582 28500364 + NUDT15 chr13 48037726 48047221 + ADGRL1 chr19 14147743 14206187 - RER1 chr1 2391775 2405442 + EIF4H chr7 74174245 74197101 + MAFK chr7 1530702 1543043 + PLXNA3 chrX 154458281 154477779 + TOMM40 chr19 44890569 44903689 + HAUS1 chr18 46104378 46128333 + INPP5A chr10 132537787 132783480 + FTL chr19 48965309 48966879 + HINFP chr11 119121580 119136059 + MT-CO2 chrMT 7586 8269 + TUBB chr6 30720352 30725426 + SEH1L chr18 12947133 12987536 + VCP chr9 35056064 35072627 - B3GNT5 chr3 183253253 183298504 + miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AL121992.1 chr1 15586136 15603626 - AL121987.1 chr1 160062461 160080769 + AL645608.2 chr1 911435 914948 + MALAT1 chr11 65497688 65506516 + SLC16A1-AS1 chr1 112956415 113047055 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.