exRNAdisease

Entry Detail

---



General Information

Database ID: exR0755363 RNA Name: ACD RNA Type: mRNA Chromosome: chr16 Starnd: - Coordinate: Start Site(bp): 67657512 End Site(bp): 67660815 External Links: ENSG00000102977

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand DHX9 chr1 182839347 182887982 + DGCR2 chr22 19036282 19122454 - HSP90AB1 chr6 44246166 44253888 + AP002990.1 chr11 62559603 62591531 - ZNF23 chr16 71447597 71463095 - DUSP3 chr17 43766125 43778977 - EEF1G chr11 62559596 62574086 - SEC22C chr3 42547969 42601080 - SLC35B2 chr6 44254096 44257890 - PPM1A chr14 60245752 60299087 + CDK16 chrX 47217860 47229997 + MEPCE chr7 100428790 100434118 + FGFRL1 chr4 1009936 1026898 + NAA10 chrX 153929225 153935080 - MT-CO1 chrMT 5904 7445 + ATP6V1D chr14 67294371 67360265 - EFTUD2 chr17 44849948 44899445 - TFAM chr10 58385345 58399220 + RAF1 chr3 12583601 12664226 - MARCKSL1 chr1 32333839 32336233 - CNOT1 chr16 58519951 58629885 - FSTL3 chr19 676392 683392 + HNRNPD chr4 82352498 82374503 - PCBP2 chr12 53452102 53481162 + TSPAN9 chr12 3077355 3286564 + PSMA4 chr15 78540405 78552417 + GCN1 chr12 120127202 120194715 - COX14 chr12 50112082 50120457 + GNAS chr20 58839718 58911192 + RPS6KA1 chr1 26529761 26575030 + miRNA targets: NA circRNA targets: NA lncRNA targets: NA Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.