exRNAdisease

Entry Detail

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General Information

Database ID: exR0755382 RNA Name: ACP5 RNA Type: mRNA Chromosome: chr19 Starnd: - Coordinate: Start Site(bp): 11574660 End Site(bp): 11579008 External Links: ENSG00000102575

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ACTG1 chr17 81509971 81523847 - AL669918.1 chr6 32813767 32838822 - ATP5F1D chr19 1241746 1244825 + B2M chr15 44711487 44718877 + CCT3 chr1 156308968 156367873 - CD226 chr18 69831158 69961803 - COX4I1 chr16 85798633 85807068 + COX6C chr8 99873200 99893707 - ENO1 chr1 8861000 8879190 - GALNT6 chr12 51351247 51392867 - HLA-B chr6 31269491 31357188 - IRAK1 chrX 154010506 154019902 - LTA chr6 31572054 31574324 + NCAPD2 chr12 6493356 6531955 + NME3 chr16 1770286 1771730 - PFN1 chr17 4945652 4949061 - PPP4R3B chr2 55547292 55618880 - PRR7 chr5 177446445 177456286 + RBM33 chr7 155644451 155781485 + RNASET2 chr6 166929504 166957191 - RPL4 chr15 66498015 66524532 - SLC25A6 chrX 1386152 1392113 - SMAD2 chr18 47808957 47931146 - SNRNP40 chr1 31259568 31296788 - TAP2 chr6 32821833 32838770 - TERF2IP chr16 75647773 75761872 + UBC chr12 124911604 124917368 - miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand SNHG16 chr17 76557764 76565348 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.