exRNAdisease

Entry Detail

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General Information

Database ID: exR0755388 RNA Name: ACSL1 RNA Type: mRNA Chromosome: chr4 Starnd: - Coordinate: Start Site(bp): 184755595 End Site(bp): 184826818 External Links: ENSG00000151726

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ACOT7 chr1 6264269 6394391 - ACP6 chr1 147629652 147670524 - ALMS1 chr2 73385758 73625166 + APOBEC3G chr22 39077067 39087743 + BCAT2 chr19 48795062 48811029 - CCL22 chr16 57358783 57366189 + CHST12 chr7 2403588 2448484 + CPNE1 chr20 35626031 35664956 - DDB1 chr11 61299451 61342596 - DPYSL2 chr8 26514031 26658178 + ENOSF1 chr18 670318 712662 - FADS2 chr11 61792980 61867354 + FBL chr19 39834458 39846379 - HNRNPH1 chr5 179614178 179634784 - IMP3 chr15 75639085 75648706 - LPXN chr11 58526871 58578220 - NAA16 chr13 41311267 41377030 + POLL chr10 101578882 101588270 - PTDSS2 chr11 448268 491399 + TMEM170A chr16 75443054 75465497 - TWNK chr10 100987367 100994403 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-34a-5p chr1 9151735 9151756 - hsa-miR-205-5p chr1 209432166 209432187 + hsa-miR-34c-5p chr11 111513451 111513473 + hsa-miR-337-3p chr14 100874553 100874574 + hsa-miR-449a chr5 55170586 55170607 - hsa-miR-449b-5p chr5 55170706 55170727 - circRNA targets: NA lncRNA targets: NA Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.