exRNAdisease

Entry Detail

---



General Information

Database ID: exR0755395 RNA Name: ACSS2 RNA Type: mRNA Chromosome: chr20 Starnd: + Coordinate: Start Site(bp): 34872146 End Site(bp): 34927962 External Links: ENSG00000131069

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand RPS19 chr19 41860255 41872925 + TUBA1B chr12 49127782 49131397 - VPS26B chr11 134224671 134247788 + EIF6 chr20 35278911 35284985 - KIAA0930 chr22 45190338 45240769 - KLHDC4 chr16 87696485 87765992 - TXNL4A chr18 79970813 80033949 - TUBA1A chr12 49184795 49189080 - NDUFB1 chr14 92116122 92121917 - DUT chr15 48331011 48343373 + NUCKS1 chr1 205712822 205750182 - SIK3 chr11 116843402 117098437 - COPS7B chr2 231781671 231809254 + LMBR1 chr7 156668946 156893216 - PFN1 chr17 4945652 4949061 - SLC52A3 chr20 760080 776015 - BLOC1S4 chr4 6716174 6717664 + GDI2 chr10 5765223 5842132 - DDX5 chr17 64498254 64508199 - TPI1 chr12 6867119 6870948 + KXD1 chr19 18557762 18569387 + NDUFS7 chr19 1383527 1395589 + DPF2 chr11 65333852 65354262 + AL121753.1 chr20 35267885 35280043 - STAT5B chr17 42199177 42276707 - RPS11 chr19 49496365 49499708 + DYNLL1 chr12 120469850 120498493 + PPP6R1 chr19 55229779 55259017 - STAU1 chr20 49113339 49188367 - HSP90AB1 chr6 44246166 44253888 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-18a-5p chr13 91350756 91350778 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AL022311.1 chr22 37876148 37895563 + AL022332.1 chr22 25279529 25282674 - GAS5 chr1 173858559 173868882 - LINC01405 chr12 110934590 110959093 + MIR17HG chr13 91347820 91354579 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.