exRNAdisease

Entry Detail

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General Information

Database ID: exR0755396 RNA Name: ACSS3 RNA Type: mRNA Chromosome: chr12 Starnd: + Coordinate: Start Site(bp): 80936414 End Site(bp): 81261210 External Links: ENSG00000111058

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand TRAM1L1 chr4 117083554 117085576 - NMNAT2 chr1 183248237 183418380 - EPB41L2 chr6 130839347 131063322 - CNST chr1 246566444 246668595 + TJP1 chr15 29699367 29968865 - UBL7 chr15 74445977 74461182 - SENP3-EIF4A1 chr17 7563287 7578715 + UBE2E1 chr3 23805955 23891640 + MIDN chr19 1248553 1259140 + TUBB chr6 30720352 30725426 + KXD1 chr19 18557762 18569387 + U2SURP chr3 142964497 143060725 + TPI1 chr12 6867119 6870948 + UBE2D2 chr5 139526431 139628434 + SCAPER chr15 76347904 76905444 - PTGES3 chr12 56663341 56688408 - DEK chr6 18223860 18264548 - OPRD1 chr1 28812142 28871267 + POLR1D chr13 27620742 27744237 + RPS23 chr5 82273320 82278396 - EIF4A1 chr17 7572706 7579006 + RHEB chr7 151466012 151520120 - RPS6KC1 chr1 213051233 213274774 + ME2 chr18 50879080 50954257 + ARF4 chr3 57571363 57598220 - ENO1 chr1 8861000 8879190 - SWT1 chr1 185157080 185291781 + CRABP2 chr1 156699606 156705816 - NONO chrX 71283192 71301168 + HMGN4 chr6 26538366 26546933 + miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC016876.2 chr17 7581964 7584086 - NIFK-AS1 chr2 121649320 121728563 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.