exRNAdisease

Entry Detail

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General Information

Database ID: exR0755399 RNA Name: ACTC1 RNA Type: mRNA Chromosome: chr15 Starnd: - Coordinate: Start Site(bp): 34790230 End Site(bp): 34795549 External Links: ENSG00000159251

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand SLC12A6 chr15 34229784 34338060 - PRKDC chr8 47773111 47960178 - POTEI chr2 130459455 130509707 - VAT1 chr17 43014607 43025123 - IL16 chr15 81159575 81314058 + PCNA chr20 5114953 5126626 - FAM185A chr7 102748971 102809225 + RPS17 chr15 82536750 82540459 - EDC3 chr15 74630558 74696292 - TBC1D9B chr5 179862066 179907859 - ZBTB45 chr19 58513530 58538911 - B2M chr15 44711487 44718877 + EID1 chr15 48878134 48880173 + ENO2 chr12 6913745 6923698 + UBQLN4 chr1 156035299 156053798 - ATP1A1 chr1 116372668 116410261 + AP1G1 chr16 71729000 71809201 - SNRPB chr20 2461634 2470853 - RPL26 chr17 8377516 8383213 - G6PD chrX 154531391 154547572 - CAND1 chr12 67269358 67319953 + TPI1 chr12 6867119 6870948 + AC245033.1 chr15 82536788 82573194 - ACTR1A chr10 102461881 102502712 - CASC4 chr15 44288719 44415758 + ACTA1 chr1 229431245 229434098 - SORL1 chr11 121452314 121633763 + JTB chr1 153974269 153977674 - VPS51 chr11 65089324 65111862 + SERF2 chr15 43777087 43802589 + miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC019205.1 chr6 73263212 73301789 + AC105339.2 chr15 82752884 82757208 + AC139149.1 chr17 81514047 81527776 + AC012379.1 chr15 48783190 48784121 + AC135178.2 chr17 8318088 8318712 - AL359924.1 chr1 237862175 237928321 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.