exRNAdisease

Entry Detail

---



General Information

Database ID: exR0755405 RNA Name: ACTR10 RNA Type: mRNA Chromosome: chr14 Starnd: + Coordinate: Start Site(bp): 58200080 End Site(bp): 58235636 External Links: ENSG00000131966

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand HIBCH chr2 190189735 190344193 - CCNG1 chr5 163437569 163446151 + PPP2CA chr5 134194332 134226073 - TOMM20 chr1 235109341 235128837 - ACTB chr7 5527148 5563784 - APP chr21 25880550 26171128 - PTK2B chr8 27311482 27459391 + CTDSP2 chr12 57819927 57846729 - SLC6A9 chr1 43991500 44031467 - B2M chr15 44711487 44718877 + RPS20 chr8 56067295 56074581 - NUDC chr1 26900238 26946871 + AURKA chr20 56369389 56392337 - PABPC3 chr13 25095868 25099254 + TUBA3C chr13 19173772 19181824 - UBA6 chr4 67612652 67701155 - CAND1 chr12 67269358 67319953 + MGRN1 chr16 4616493 4690974 + ARF1 chr1 228082660 228099212 + ALDOA chr16 30064164 30070457 + MTRNR2L12 chr3 96617188 96618236 - PBX1 chr1 164555584 164899296 + PRKCI chr3 170222424 170305977 + LRRC20 chr10 70298970 70382650 - CCNC chr6 99542387 99568825 - SMARCC1 chr3 47585269 47782106 - TSPAN15 chr10 69451465 69507666 + NID1 chr1 235975830 236065109 - CAMK2G chr10 73812501 73874591 - AIF1L chr9 131096476 131123152 + miRNA targets: NA circRNA targets: NA lncRNA targets: NA Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.