exRNAdisease

Entry Detail

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General Information

Database ID: exR0755412 RNA Name: ACTR6 RNA Type: mRNA Chromosome: chr12 Starnd: + Coordinate: Start Site(bp): 100199122 End Site(bp): 100241865 External Links: ENSG00000075089

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ANKFY1 chr17 4163821 4263995 - DDX24 chr14 94048287 94081212 - AP002990.1 chr11 62559603 62591531 - CD52 chr1 26317958 26320523 + HNRNPC chr14 21209136 21269494 - RPS23 chr5 82273320 82278396 - NAGK chr2 71064344 71079808 + EEF1G chr11 62559596 62574086 - RPL13 chr16 89560657 89566828 + IGF2 chr11 2129112 2141238 - UBE2D3 chr4 102794383 102868896 - CD81 chr11 2376177 2397419 + VSIG10 chr12 118063593 118136026 - TMEM123 chr11 102396332 102470384 - ACTB chr7 5527148 5563784 - GYG2 chrX 2828822 2882820 + RAB35 chr12 120095099 120117502 - NSUN5 chr7 73302516 73308826 - HLA-C chr6 31268749 31272130 - ATP6AP2 chrX 40579372 40606848 + FTH1 chr11 61959718 61967634 - MTRNR2L12 chr3 96617188 96618236 - ADH5 chr4 99070978 99088801 - CLEC2D chr12 9664969 9699553 + NONO chrX 71283192 71301168 + RPS7 chr2 3575260 3580920 + ZNF90 chr19 20077994 20127076 + SLAMF1 chr1 160608106 160647295 - ST8SIA1 chr12 22063773 22437041 - YIPF3 chr6 43511832 43516985 - miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-6747-3p chr11 62567011 62567031 - circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand LINC02539 chr6 137730170 137792835 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.