exRNAdisease

Entry Detail

---



General Information

Database ID: exR0755414 RNA Name: ACVR1 RNA Type: mRNA Chromosome: chr2 Starnd: - Coordinate: Start Site(bp): 157736444 End Site(bp): 157876330 External Links: ENSG00000115170

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand BCAT1 chr12 24810024 24949101 - BRINP1 chr9 119153458 119369435 - CIT chr12 119685791 119877320 - EIF4B chr12 53006158 53042209 + EWSR1 chr22 29268009 29300525 + IFITM2 chr11 307631 315272 + KPNA4 chr3 160495007 160565571 - MAZ chr16 29806106 29811164 + MRPS5 chr2 95085369 95149434 - MT-CO3 chrMT 9207 9990 + NSL1 chr1 212726153 212791782 - PEF1 chr1 31629866 31644896 - RPS27A chr2 55231903 55235853 + SKAP2 chr7 26667068 26995239 - TCF12 chr15 56918623 57299281 + ZBED6 chr1 203795714 203854999 + ZC3H11A chr1 203795654 203854999 + ZNF468 chr19 52838010 52857649 - miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-876-5p chr9 28863675 28863696 - circRNA targets: NA lncRNA targets: NA Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.