exRNAdisease

Entry Detail

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General Information

Database ID: exR0755417 RNA Name: ACVR2B RNA Type: mRNA Chromosome: chr3 Starnd: + Coordinate: Start Site(bp): 38453890 End Site(bp): 38493142 External Links: ENSG00000114739

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand SF3A3 chr1 37956975 37990075 - LSM4 chr19 18306230 18323274 - DDX17 chr22 38483438 38507660 - MTCH1 chr6 36968141 36986298 - BCL6 chr3 187721377 187745725 - TCOF1 chr5 150357629 150400308 + LZTS2 chr10 100996618 101007836 + PACSIN2 chr22 42835412 43015149 - CBY1 chr22 38656636 38673854 + ZDBF2 chr2 206274663 206314427 + UNC45A chr15 90930180 90954093 + FAM111B chr11 59107185 59127412 + UBE3B chr12 109477402 109536705 + DNAAF2 chr14 49625174 49635230 - GPAM chr10 112149865 112215377 - CHRFAM7A chr15 30357766 30393849 - SORD chr15 45023181 45077185 + HSPA5 chr9 125234853 125241343 - MT-CO3 chrMT 9207 9990 + TBC1D15 chr12 71839707 71927248 + MYO7A chr11 77128246 77215241 + TUBA1B chr12 49127782 49131397 - HNRNPAB chr5 178204533 178211163 + MRPL12 chr17 81703367 81707517 + SNRPN chr15 24823637 24978723 + AL138752.2 chr9 37588413 38068687 - NT5DC2 chr3 52524385 52535054 - ISOC1 chr5 129094749 129114028 + SLC25A17 chr22 40769630 40819399 - CRMP1 chr4 5748084 5893086 - miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-221-3p chrX 45746180 45746202 - hsa-miR-423-5p chr17 30117095 30117117 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC090948.2 chr3 16339308 16339871 + AD000090.1 chr19 35557956 35581954 + LINC01578 chr15 92819540 92899701 + LINC02035 chr3 122886941 122892416 + NEAT1 chr11 65422774 65445540 + XIST chrX 73820649 73852723 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.