exRNAdisease

Entry Detail

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General Information

Database ID: exR0755421 RNA Name: ADAL RNA Type: mRNA Chromosome: chr15 Starnd: + Coordinate: Start Site(bp): 43330657 End Site(bp): 43354555 External Links: ENSG00000168803

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand EIF2S3 chrX 24054946 24078810 + EIF4B chr12 53006158 53042209 + GINS4 chr8 41529218 41545030 + HLA-F chr6 29722775 29738528 + MZB1 chr5 139387467 139390081 - NADK chr1 1751232 1780457 - PIGS chr17 28553383 28571794 - RNF24 chr20 3927309 4015558 - RPL10 chrX 154389955 154409168 + RPL13 chr16 89560657 89566828 + RPL37A chr2 216498825 216579180 + SALL2 chr14 21521080 21537216 - SERINC1 chr6 122443351 122471807 - SFRP2 chr4 153780591 153789083 - UAP1L1 chr9 137077517 137084539 + WDR62 chr19 36054881 36105108 + ZNF431 chr19 21142024 21196053 + miRNA targets: NA circRNA targets: NA lncRNA targets: NA Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.