exRNAdisease

Entry Detail

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General Information

Database ID: exR0755422 RNA Name: ADAM10 RNA Type: mRNA Chromosome: chr15 Starnd: - Coordinate: Start Site(bp): 58588809 End Site(bp): 58749791 External Links: ENSG00000137845

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand RPS11 chr19 49496365 49499708 + THUMPD3 chr3 9362971 9386791 + ATXN3 chr14 92044496 92106621 - NUDT21 chr16 56429133 56452199 - MORF4L1 chr15 78810487 78898139 + RPS24 chr10 78033760 78056813 + SMARCC1 chr3 47585269 47782106 - YY1 chr14 100238298 100282788 + RB1CC1 chr8 52622458 52745843 - SPATS2L chr2 200305881 200482264 + MAPK9 chr5 180233143 180292099 - RFLNA chr12 123973241 124316024 + TCTN3 chr10 95663396 95694143 - RPL13 chr16 89560657 89566828 + MRPL30 chr2 99181152 99199561 + METTL2B chr7 128476729 128506602 + MPZL1 chr1 167721192 167791919 + OSBP chr11 59574398 59615774 - PBX1 chr1 164555584 164899296 + TAB2 chr6 149218641 149411613 + RBM42 chr19 35629030 35637686 + WBP11 chr12 14784582 14803486 - TMEM189 chr20 50118254 50153734 - TRIM28 chr19 58544064 58550722 + GNAI3 chr1 109548615 109600195 + ANXA6 chr5 151100706 151157785 - XRCC6 chr22 41621119 41664048 + PGM3 chr6 83161150 83193936 - ACTN4 chr19 38647649 38731589 + E2F2 chr1 23506438 23531233 - miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-1248 chr3 186786675 186786701 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AL096870.2 chr14 24209646 24215987 - AC068790.8 chr12 123973215 124088594 + AL645465.1 chr1 244375100 244409592 - FGD5-AS1 chr3 14920347 14948424 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.