exRNAdisease

Entry Detail

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General Information

Database ID: exR0755425 RNA Name: ADAM19 RNA Type: mRNA Chromosome: chr5 Starnd: - Coordinate: Start Site(bp): 157395534 End Site(bp): 157575775 External Links: ENSG00000135074

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AGO4 chr1 35808016 35857890 + AICDA chr12 8602170 8612867 - BZW1 chr2 200810594 200827338 + CALM3 chr19 46601074 46610782 + DDX17 chr22 38483438 38507660 - EIF3J chr15 44537125 44563029 + FKBP1A chr20 1368978 1393172 - FOCAD chr9 20658309 20995955 + GTF3C2 chr2 27325849 27357034 - IGFBP2 chr2 216632828 216664436 + LRP5L chr22 25351418 25405377 - MGST3 chr1 165631213 165661796 + MYH9 chr22 36281277 36388067 - NDST1 chr5 150485818 150558211 + PRDX5 chr11 64318121 64321811 + PSMD8 chr19 38374536 38383824 + PTPN6 chr12 6946468 6961316 + RAB1B chr11 66268590 66277492 + RNF5 chr6 32178405 32180793 + RPL13 chr16 89560657 89566828 + SLC38A1 chr12 46183063 46270017 - SMARCA4 chr19 10960825 11079426 + STMN1 chr1 25884181 25906991 - TATDN2 chr3 10248023 10281218 + TMEM60 chr7 77793728 77798434 - VPS18 chr15 40894450 40903975 + ZNF354B chr5 178859953 178888122 + ZNHIT2 chr11 65116403 65117701 - miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-423-5p chr17 30117095 30117117 + circRNA targets: NA lncRNA targets: NA Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.