exRNAdisease

Entry Detail

---



General Information

Database ID: exR0755432 RNA Name: ADAM9 RNA Type: mRNA Chromosome: chr8 Starnd: + Coordinate: Start Site(bp): 38996869 End Site(bp): 39105261 External Links: ENSG00000168615

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand CAPNS1 chr19 36139953 36150353 + ARID3B chr15 74541177 74598131 + TOR1AIP2 chr1 179839967 179877803 - MFSD14C chr9 96887373 97013708 - UHRF1 chr19 4903080 4962154 + PCNP chr3 101574180 101594465 + LDHA chr11 18394560 18408425 + ST8SIA1 chr12 22063773 22437041 - PNMA8A chr19 46466491 46471563 - ORC2 chr2 200908977 200963680 - EEF2 chr19 3976056 3985463 - RPA1 chr17 1829702 1900082 + TCEA1 chr8 53966552 54022456 - TMSB4X chrX 12975110 12977227 + RPL18 chr19 48615328 48619184 - FNIP1 chr5 131641714 131797063 - CANX chr5 179678628 179731641 + POP1 chr8 98117293 98159835 + PLXNA1 chr3 126988594 127037392 + CDK4 chr12 57747727 57756013 - KNTC1 chr12 122527246 122626396 + MT-CO1 chrMT 5904 7445 + RPL4 chr15 66498015 66524532 - TRA2B chr3 185914558 185938103 - EVX2 chr2 176077472 176083913 - NDUFB7 chr19 14566078 14572066 - ACRBP chr12 6638075 6647433 - PRRC1 chr5 127517609 127555089 + HSP90AB1 chr6 44246166 44253888 + LPCAT3 chr12 6976185 7018477 - miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AP001496.2 chr18 5232876 5238526 - NEAT1 chr11 65422774 65445540 + PIK3CD-AS2 chr1 9672426 9687555 - SLFNL1-AS1 chr1 41014590 41043890 + XIST chrX 73820649 73852723 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.