exRNAdisease

Entry Detail

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General Information

Database ID: exR0755433 RNA Name: ADAMTS10 RNA Type: mRNA Chromosome: chr19 Starnd: - Coordinate: Start Site(bp): 8580240 End Site(bp): 8610735 External Links: ENSG00000142303

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AC010422.3 chr19 12643831 12648397 - ALDOA chr16 30064164 30070457 + ATXN2L chr16 28823035 28837237 + BIN1 chr2 127048027 127107288 - CD59 chr11 33703010 33736491 - HDDC3 chr15 90929964 90935196 - HNRNPDL chr4 82422564 82430408 - HSP90AB1 chr6 44246166 44253888 + LAPTM4B chr8 97775057 97853013 + LARGE1 chr22 33162226 33922841 - MTOR chr1 11106535 11262551 - PTMA chr2 231706895 231713541 + RPL18A chr19 17859910 17864153 + TPI1 chr12 6867119 6870948 + TSPAN4 chr11 842812 867116 + TUBB chr6 30720352 30725426 + miRNA targets: NA circRNA targets: NA lncRNA targets: NA Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.