exRNAdisease

Entry Detail

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General Information

Database ID: exR0755446 RNA Name: ADAT1 RNA Type: mRNA Chromosome: chr16 Starnd: - Coordinate: Start Site(bp): 75596981 End Site(bp): 75623300 External Links: ENSG00000065457

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand BFAR chr16 14632931 14669236 + CD22 chr19 35319261 35347361 + CD48 chr1 160678746 160711831 - CFDP1 chr16 75293698 75433503 - CREB3L2 chr7 137874979 138002086 - FUT11 chr10 73772276 73780251 + HNRNPM chr19 8444767 8489114 + IGF2 chr11 2129112 2141238 - KCNC3 chr19 50311937 50333515 - KMT2B chr19 35717973 35738878 + MAEA chr4 1289887 1340147 + METRN chr16 715118 719655 + NME1-NME2 chr17 51153590 51171744 + NME2 chr17 51165435 51171747 + NT5DC2 chr3 52524385 52535054 - PAK1 chr11 77321707 77474635 - RPP14 chr3 58306247 58324695 + STT3A chr11 125591712 125625215 + miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC025287.1 chr16 75541399 75608445 - KCNQ1OT1 chr11 2608328 2699994 - MALAT1 chr11 65497688 65506516 + ZNF710-AS1 chr15 90074512 90082207 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.