exRNAdisease

Entry Detail

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General Information

Database ID: exR0755451 RNA Name: ADCY6 RNA Type: mRNA Chromosome: chr12 Starnd: - Coordinate: Start Site(bp): 48766194 End Site(bp): 48789037 External Links: ENSG00000174233

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand MACF1 chr1 39081316 39487177 + SLC25A29 chr14 100291116 100306547 - HSP90AB1 chr6 44246166 44253888 + CALM1 chr14 90396502 90408268 + PRRT4 chr7 128350325 128361685 - LCMT1 chr16 25111731 25178231 + FLNA chrX 154348524 154374638 - TPM4 chr19 16067021 16103002 + FADS2 chr11 61792980 61867354 + MYBBP1A chr17 4538897 4555631 - UBB chr17 16380798 16382745 + RNF167 chr17 4940008 4945222 + PUS1 chr12 131929200 131945896 + LRCH4 chr7 100574011 100586129 - SELENOP chr5 42799880 42887392 - ARID1A chr1 26693236 26782104 + PEX19 chr1 160276812 160286348 - IGF2 chr11 2129112 2141238 - FNDC3B chr3 172039578 172401669 + HUWE1 chrX 53532096 53686728 - PDCD7 chr15 65117379 65133808 - LENG8 chr19 54448887 54462037 + SYNM chr15 99098217 99135593 + EME2 chr16 1772810 1781708 + FNTB chr14 64986895 65062652 + SMARCD1 chr12 50085200 50100707 + SNTB2 chr16 69187129 69309052 + ZNF628 chr19 55476617 55484487 + SNRPF chr12 95858928 95903828 + TAZ chrX 154411524 154421726 + miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC069281.2 chr7 100572232 100578700 - AC138761.1 chr17 22266395 22288301 + XIST chrX 73820649 73852723 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.