exRNAdisease

Entry Detail

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General Information

Database ID: exR0755452 RNA Name: ADCY7 RNA Type: mRNA Chromosome: chr16 Starnd: + Coordinate: Start Site(bp): 50246137 End Site(bp): 50318135 External Links: ENSG00000121281

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ACTG1 chr17 81509971 81523847 - ADCY4 chr14 24318349 24335093 - CNTROB chr17 7932101 7949920 + FTL chr19 48965309 48966879 + GLUD1 chr10 87050202 87094843 - GSTP1 chr11 67583742 67586656 + HSPE1 chr2 197500140 197503449 + MRPS6 chr21 34073224 34143034 + PNMA8A chr19 46466491 46471563 - RPL4 chr15 66498015 66524532 - RPL7A chr9 133348218 133351426 + SBNO2 chr19 1107637 1174268 - SLC5A3 chr21 34073578 34106260 + SRGN chr10 69088103 69104805 + SYNGR2 chr17 78168558 78173527 + TMEM189-UBE2V1 chr20 50081124 50153637 - TPT1 chr13 45333471 45341370 - TTC38 chr22 46267961 46294008 + UBE2V1 chr20 50081124 50115959 - ZFP36L1 chr14 68787660 68796253 - ZHX3 chr20 41178448 41317672 - miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AP000317.2 chr21 34073592 34360033 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.