exRNAdisease

Entry Detail

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General Information

Database ID: exR0755457 RNA Name: ADD3 RNA Type: mRNA Chromosome: chr10 Starnd: + Coordinate: Start Site(bp): 109996368 End Site(bp): 110135565 External Links: ENSG00000148700

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ZNF90 chr19 20077994 20127076 + SLC2A3 chr12 7919230 7936187 - C16orf72 chr16 9091644 9121635 + SMARCB1 chr22 23786931 23838008 + MAGI1 chr3 65353525 66038834 - STK26 chrX 132023302 132075943 + GGH chr8 63015079 63038806 - AASS chr7 122073549 122144255 - AC011462.1 chr19 41350853 41425001 + COPS3 chr17 17246616 17281273 - HDGF chr1 156742109 156766925 - ATP6V1G1 chr9 114587769 114598879 + TIMELESS chr12 56416363 56449426 - CNTNAP2 chr7 146116002 148420998 + CNTN2 chr1 205042937 205078289 + TBCD chr17 82752065 82945914 + TM9SF4 chr20 32109714 32167258 + EXOSC8 chr13 36998816 37009614 + KHNYN chr14 24429286 24441843 + CLTA chr9 36190856 36304781 + MEST chr7 130486171 130506465 + MT-CO1 chrMT 5904 7445 + SELENOF chr1 86862445 86914424 - TOX4 chr14 21476597 21499175 + TMED5 chr1 93149742 93180516 - HILPDA chr7 128455849 128458418 + BCAS3 chr17 60677453 61392838 + RBMX chrX 136848004 136880764 - MRPS23 chr17 57834781 57850056 - TPT1 chr13 45333471 45341370 - miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC002470.2 chr22 20979462 20998121 + AC020928.1 chr19 36773112 36777078 + MALAT1 chr11 65497688 65506516 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.