exRNAdisease

Entry Detail

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General Information

Database ID: exR0755459 RNA Name: ADGRA3 RNA Type: mRNA Chromosome: chr4 Starnd: - Coordinate: Start Site(bp): 22345071 End Site(bp): 22516066 External Links: ENSG00000152990

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand SPTLC3 chr20 13008972 13169103 + EP400 chr12 131949942 132080460 + PMM1 chr22 41576900 41589871 - EHD4 chr15 41895933 41972557 - DBNDD1 chr16 90004871 90020128 - FAM49B chr8 129839593 130017129 - CANX chr5 179678628 179731641 + CLIC4 chr1 24745382 24844321 + PTMA chr2 231706895 231713541 + SLC35A4 chr5 140564828 140569100 + USP53 chr4 119212587 119295517 + SLC2A1 chr1 42925375 42958868 - FTL chr19 48965309 48966879 + TMEM184B chr22 38219291 38273010 - SLC25A11 chr17 4937130 4940053 - CXXC4 chr4 104468308 104494901 - YLPM1 chr14 74763316 74859435 + FNTA chr8 43034194 43085788 + ACACA chr17 37084992 37406836 - ZBTB6 chr9 122908056 122913323 - ATIC chr2 215311956 215349773 + MTCH1 chr6 36968141 36986298 - EPN1 chr19 55675226 55709858 + EIF3A chr10 119033670 119080823 - YWHAZ chr8 100916523 100953388 - STOM chr9 121338987 121370304 - DHCR24 chr1 54849627 54887195 - RPLP1 chr15 69452814 69456205 + MT-ATP8 chrMT 8366 8572 + ZMYM4 chr1 35268709 35422058 + miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC009022.1 chr16 69976297 70065948 - AC079949.1 chr12 127142029 127146532 - HLA-F-AS1 chr6 29726601 29749049 - LINC00458 chr13 54115783 54142319 - MUC20-OT1 chr3 195658062 195739964 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.