exRNAdisease

Entry Detail

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General Information

Database ID: exR0755470 RNA Name: ADGRG2 RNA Type: mRNA Chromosome: chrX Starnd: - Coordinate: Start Site(bp): 18989307 End Site(bp): 19122637 External Links: ENSG00000173698

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand PFKL chr21 44300051 44327376 + CTSH chr15 78921058 78949574 - FASN chr17 82078338 82098294 - ANKHD1 chr5 140401814 140539856 + HMGA1 chr6 34236873 34246231 + PPP1R9B chr17 50133737 50150677 - FLAD1 chr1 154983338 154993111 + CBX3 chr7 26201162 26213607 + ABCA3 chr16 2275881 2340746 - SH3D19 chr4 151102751 151325632 - KPNA1 chr3 122421902 122514945 - HLA-B chr6 31269491 31357188 - NPIPB3 chr16 21402237 21448567 - ANKHD1-EIF4EBP3 chr5 140401908 140549569 + AC120114.4 chr16 29817239 29830627 + XPO6 chr16 28097979 28211920 - ZNF623 chr8 143636013 143656418 + PCGF2 chr17 38733898 38749817 - BDP1 chr5 71455651 71567820 + LRP3 chr19 33177603 33208864 + RTL6 chr22 44492583 44498233 - HMG20B chr19 3572777 3579088 + E2F2 chr1 23506438 23531233 - ARID1B chr6 156776020 157210779 + TNPO2 chr19 12699194 12724011 - WRNIP1 chr6 2765393 2786952 + EIF4H chr7 74174245 74197101 + LRWD1 chr7 102464956 102473168 + PIM2 chrX 48913182 48919024 - TMEM184B chr22 38219291 38273010 - miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC008738.7 chr19 33207129 33207639 + AD000090.1 chr19 35557956 35581954 + CYTOR chr2 87454781 87636740 + XIST chrX 73820649 73852723 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.