exRNAdisease

Entry Detail

---



General Information

Database ID: exR0755475 RNA Name: ADGRL2 RNA Type: mRNA Chromosome: chr1 Starnd: + Coordinate: Start Site(bp): 81306160 End Site(bp): 81992436 External Links: ENSG00000117114

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand PRPF4B chr6 4021267 4064983 + RPS18 chr6 33272075 33276511 + RBM39 chr20 35701347 35742312 - CBX3 chr7 26201162 26213607 + NSD1 chr5 177133025 177300215 + FUS chr16 31180110 31194871 + ATP5F1B chr12 56638175 56645984 - FAM199X chrX 104166453 104195902 + PSMA6 chr14 35278633 35317493 + LMO4 chr1 87328880 87348923 + RPL27A chr11 8682788 8714759 + KIF5B chr10 32009015 32056425 - RBM14-RBM4 chr11 66616626 66646469 + FOXO3 chr6 108559835 108684774 + RBM4 chr11 66638617 66668374 + MRFAP1 chr4 6640091 6642745 + CPEB3 chr10 92046692 92291078 - MED18 chr1 28329002 28335965 + PCID2 chr13 113177536 113208715 - ASNSD1 chr2 189661385 189670831 + TTC7A chr2 46916157 47076137 + YBX1 chr1 42682418 42703805 + POM121C chr7 75416786 75486299 - TXNL4A chr18 79970813 80033949 - MARCKS chr6 113857345 113863475 + EDARADD chr1 236348257 236502915 + PUM1 chr1 30931506 31065991 - UBQLN1 chr9 83659968 83707958 - ANAPC2 chr9 137174784 137188560 - GNAS chr20 58839718 58911192 + miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AD000090.1 chr19 35557956 35581954 + AC022034.1 chr8 53493523 53524336 - JPX chrX 73944182 74070408 + NEAT1 chr11 65422774 65445540 + XIST chrX 73820649 73852723 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.