exRNAdisease

Entry Detail

---



General Information

Database ID: exR0755478 RNA Name: ADGRV1 RNA Type: mRNA Chromosome: chr5 Starnd: + Coordinate: Start Site(bp): 90529344 End Site(bp): 91164437 External Links: ENSG00000164199

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand TTC37 chr5 95461755 95555007 - PODXL2 chr3 127629185 127672802 + DVL1 chr1 1335276 1349418 - RPL18A chr19 17859910 17864153 + TACO1 chr17 63600882 63608365 + CANX chr5 179678628 179731641 + MGAT1 chr5 180784782 180815652 - TMEM60 chr7 77793728 77798434 - SHROOM3 chr4 76435229 76783253 + SETD5 chr3 9397615 9479240 + TAF1 chrX 71366239 71532374 + MT-ND1 chrMT 3307 4262 + PLXNA3 chrX 154458281 154477779 + PSMD12 chr17 67337916 67366605 - NEURL4 chr17 7315628 7329393 - SNRNP40 chr1 31259568 31296788 - MTHFD2 chr2 74198610 74217565 + CTNND1 chr11 57753243 57819546 + WDR33 chr2 127701027 127811187 - OPA1 chr3 193593144 193697811 + CSNK1G1 chr15 64165525 64356173 - ORAI2 chr7 102433106 102456825 + HCN3 chr1 155277463 155289848 + TUBB chr6 30720352 30725426 + RSAD1 chr17 50478860 50485974 + FANCL chr2 58159243 58241372 - CNNM1 chr10 99329356 99394330 + PHRF1 chr11 576470 612222 + HNRNPA1L2 chr13 52642425 52643796 + PLAGL2 chr20 32192504 32207743 - miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC021504.1 chr18 41465783 41632185 - AC106798.1 chr5 67699429 67902600 - LINC02428 chr4 103255822 103454667 + XIST chrX 73820649 73852723 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.