exRNAdisease

Entry Detail

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General Information

Database ID: exR0755481 RNA Name: ADH5 RNA Type: mRNA Chromosome: chr4 Starnd: - Coordinate: Start Site(bp): 99070978 End Site(bp): 99088801 External Links: ENSG00000197894

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand GALNT2 chr1 230057990 230282122 + CLPTM1 chr19 44954585 44993341 + BUB1B chr15 40161023 40221136 + MAD1L1 chr7 1815793 2233243 - PSAP chr10 71816298 71851325 - RSAD1 chr17 50478860 50485974 + PTPN6 chr12 6946468 6961316 + ACTR6 chr12 100199122 100241865 + SRP68 chr17 76038775 76072517 - CEBPZ chr2 37201612 37231596 - SEC61A1 chr3 128051641 128071683 + TYRO3 chr15 41557675 41583589 + RPS19 chr19 41860255 41872925 + SMARCA4 chr19 10960825 11079426 + ILF2 chr1 153661788 153671028 - NUDCD3 chr7 44379119 44490658 - SEC22A chr3 123201927 123274136 + RAN chr12 130872037 130877678 + OTX2 chr14 56799905 56816693 - RPL15 chr3 23916545 23924374 + SLX1A chr16 30193887 30197561 + C5orf30 chr5 103258763 103278660 + TUBB chr6 30720352 30725426 + WDFY1 chr2 223855716 223945357 - AL136454.1 chr1 192716132 192716653 + VIM chr10 17228241 17237593 + TAF6 chr7 100107070 100119841 - HMGA1 chr6 34236873 34246231 + PABPC1 chr8 100685816 100722809 - VCL chr10 73995193 74121363 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-1825 chr20 32237830 32237847 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand C5orf17 chr5 23951348 24178263 + OXCT1-AS1 chr5 41869927 41872241 + SLX1A-SULT1A3 chr16 30193892 30204310 + SNHG15 chr7 44983023 44986961 - TUG1 chr22 30969245 30979395 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.