exRNAdisease

Entry Detail

---



General Information

Database ID: exR0755482 RNA Name: ADI1 RNA Type: mRNA Chromosome: chr2 Starnd: - Coordinate: Start Site(bp): 3497366 End Site(bp): 3519531 External Links: ENSG00000182551

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ENO3 chr17 4948092 4957131 + GNL2 chr1 37566816 37595937 - ZNF485 chr10 43606419 43617904 + CYTH2 chr19 48469208 48482314 + APP chr21 25880550 26171128 - RPL36 chr19 5674947 5691875 + SLC44A2 chr19 10602457 10644557 + PAICS chr4 56435741 56464579 + TMSB4X chrX 12975110 12977227 + RPS14 chr5 150442635 150449739 - SERPING1 chr11 57597387 57614848 + STC2 chr5 173314713 173329503 - LIMS1 chr2 108534355 108687246 + SMARCA4 chr19 10960825 11079426 + TTLL6 chr17 48762235 48817214 - MORF4L2 chrX 103675496 103688158 - ADD3 chr10 109996368 110135565 + SLC11A2 chr12 50979401 51028566 - RWDD3 chr1 95234210 95247225 + HNRNPAB chr5 178204533 178211163 + QPRT chr16 29663279 29698699 + TCF7L1 chr2 85133392 85310387 + CIZ1 chr9 128161251 128204383 - SFSWAP chr12 131711081 131799737 + MFN1 chr3 179347709 179394936 + OCIAD1 chr4 48805212 48861817 + CCT7 chr2 73233420 73253021 + VANGL2 chr1 160400564 160428670 + U2AF1L5 chr21 6484623 6499261 - SNX3 chr6 108211222 108261246 - miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC009446.1 chr8 71675300 71702786 + AC022400.6 chr10 73703735 73713581 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.