exRNAdisease

Entry Detail

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General Information

Database ID: exR0755485 RNA Name: ADK RNA Type: mRNA Chromosome: chr10 Starnd: + Coordinate: Start Site(bp): 74151202 End Site(bp): 74709963 External Links: ENSG00000156110

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand CLTC chr17 59619689 59696956 + CORO1C chr12 108645109 108731596 - BCL2L1 chr20 31664452 31723989 - C12orf57 chr12 6942978 6946003 + IFI6 chr1 27666064 27672198 - RAB11FIP3 chr16 425649 523011 + GDI2 chr10 5765223 5842132 - GRWD1 chr19 48445841 48457022 + BCKDHA chr19 41397808 41425002 + DGKZ chr11 46332905 46380554 + IGF2 chr11 2129112 2141238 - PRMT1 chr19 49675786 49689029 + GJA1 chr6 121435595 121449727 + KRT19 chr17 41523617 41528308 - HLA-DPA1 chr6 33064569 33080775 - EIF3E chr8 108201216 108435333 - INO80B-WBP1 chr2 74455088 74460884 + TRIO chr5 14143342 14532128 + MTRNR2L8 chr11 10507894 10509186 - PTPN1 chr20 50510321 50585241 + ZNF664 chr12 123971845 124015439 + MRPL35 chr2 86199355 86213790 + CCNG1 chr5 163437569 163446151 + STAU1 chr20 49113339 49188367 - NBEAL1 chr2 203014879 203226378 + HMGN3 chr6 79201245 79234738 - RPS27L chr15 63125872 63158021 - ENO1 chr1 8861000 8879190 - UBE2J2 chr1 1253909 1273885 - TMED7 chr5 115613210 115632992 - miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC007952.4 chr17 19112000 19112636 - AC132217.1 chr11 2129121 2129964 - AD000090.1 chr19 35557956 35581954 + IGF2-AS chr11 2140501 2148666 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.