exRNAdisease

Entry Detail

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General Information

Database ID: exR0755486 RNA Name: ADM RNA Type: mRNA Chromosome: chr11 Starnd: + Coordinate: Start Site(bp): 10305073 End Site(bp): 10307397 External Links: ENSG00000148926

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand RASIP1 chr19 48720585 48740610 - YWHAG chr7 76326799 76358991 - SCRIB chr8 143790920 143815773 - CARHSP1 chr16 8852942 8869012 - FAU chr11 65120630 65122177 - DOLK chr9 128945530 128947603 - TMEM39B chr1 32072031 32102866 + ATP13A3 chr3 194402672 194498364 - PIEZO1 chr16 88715338 88785220 - MCUB chr4 109560209 109688719 + SSR2 chr1 156009048 156020951 - ARPC3 chr12 110434823 110450422 - PSMC4 chr19 39971165 39981764 + THOC3 chr5 175917873 176034680 - PRELID3B chr20 59033145 59042809 - CBX3 chr7 26201162 26213607 + SNX19 chr11 130875436 130916509 - STAT1 chr2 190908460 191020960 - HSP90AB1 chr6 44246166 44253888 + PSMF1 chr20 1113240 1189415 + COQ10A chr12 56266858 56270966 + SRSF7 chr2 38743599 38751494 - DDIT4 chr10 72273924 72276036 + OSGIN2 chr8 89901849 89927888 + IRS4 chrX 108732482 108736409 - CENPP chr9 92325953 92620529 + LCMT1 chr16 25111731 25178231 + PACS1 chr11 66070272 66244744 + ATP1B3 chr3 141876124 141926549 + EPS15 chr1 51354263 51519266 - miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-92a-3p chrX 134169544 134169565 - hsa-miR-363-3p chrX 134169382 134169403 - hsa-miR-367-3p chr4 112647877 112647898 - hsa-miR-92b-3p chr1 155195237 155195258 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC069281.2 chr7 100572232 100578700 - AC073111.3 chr7 150379329 150410597 + PAUPAR chr11 31812307 32002405 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.