exRNAdisease

Entry Detail

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General Information

Database ID: exR0755488 RNA Name: ADORA2A RNA Type: mRNA Chromosome: chr22 Starnd: + Coordinate: Start Site(bp): 24417879 End Site(bp): 24442357 External Links: ENSG00000128271

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand TUBA1A chr12 49184795 49189080 - ILK chr11 6603708 6610874 + RPL23A chr17 28719985 28724359 + TUB chr11 8019244 8106112 + GABARAP chr17 7240008 7242449 - RETREG2 chr2 219176225 219185475 + RPS3 chr11 75399515 75422280 + LMNA chr1 156082573 156140089 + SPECC1L chr22 24270817 24417739 + IFI30 chr19 18173162 18178117 + NFKB2 chr10 102394110 102402524 + RPL9 chr4 39452521 39458949 - MX1 chr21 41420304 41459214 + EIF4B chr12 53006158 53042209 + LRFN4 chr11 66856647 66860475 + CTSH chr15 78921058 78949574 - CHCHD3 chr7 132784870 133082090 - ITGB1 chr10 32900318 33005792 - MTPN chr7 135926760 135977359 - IFFO1 chr12 6538375 6556083 - CLK3 chr15 74598500 74645414 + RPL3 chr22 39312882 39320389 - P4HB chr17 81843161 81860624 - RPS16 chr19 39433137 39435949 - VAMP5 chr2 85584431 85593406 + SPECC1L-ADORA2A chr22 24270898 24442356 + TMSB4X chrX 12975110 12977227 + MCM2 chr3 127598410 127622436 + ACTG1 chr17 81509971 81523847 - EIF3D chr22 36510855 36529184 - miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AL121832.3 chr20 62402236 62405935 - AL137127.1 chr1 19072110 19075511 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.