exRNAdisease

Entry Detail

General Information

Database ID:

exR0755500

RNA Name:

AFAP1L2

RNA Type:

mRNA

Chromosome:

chr10

Starnd:

-

Coordinate:

Start Site(bp):

114294824

End Site(bp):

114404756

External Links:

ENSG00000169129

Disease Information

Disease Name:	Glioblastoma Multiforme
Disease Category:	Cancers
MeSH ID:	D005909
Type:	Neoplasms/Neoplasms, Glandular and Epithelial
Alias:	Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID:	GSE106804
Description:	Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles
Experimental Design:	Cancer vs Control
Case Disease Type:	Glioblastoma Multiforme
Case Disease SubType:	NA
Case Sample:	Glioblastoma Multiforme
Control Sample:	Healthy
Number of Case:	13
Number of Control:	6
Number of Samples:	19

Regulatory Relationship

mRNA targets:

Gene Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
EEF1A1	chr6	73515750	73523797	-
EHMT1	chr9	137618992	137870016	+
FDFT1	chr8	11795573	11839304	+
FTL	chr19	48965309	48966879	+
KCNC4	chr1	110211343	110283100	+
KHDRBS1	chr1	32013868	32060850	+
NUP37	chr12	102073103	102120120	-
RAB5B	chr12	55973913	55996683	+
RPLP1	chr15	69452814	69456205	+
SLC2A3	chr12	7919230	7936187	-
WTIP	chr19	34481758	34512304	+

miRNA targets:

NA

circRNA targets:

NA

lncRNA targets:

lncRNA Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
ERICH6-AS1	chr3	150703564	150723005	+

Display:

Experiment Detail

GEO ID:	NA
Sample Source:	NA
Source Fraction:	NA
Platform:	NA
Method:	NA
Num of detected RNA Type:	NA
Num of detected RNAs of this Type:	NA
Sample treatment protocol:	NA
RNA Extract protocol:	NA
RNA library preparation protocol:	NA

Reference

PMID:	29330365
Title:	Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles.
Author:	Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL.
Journal:	Nat Commun. 2018 Jan 12;9(1):175.
Description:	Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.