exRNAdisease

Entry Detail

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General Information

Database ID: exR0755501 RNA Name: AFDN RNA Type: mRNA Chromosome: chr6 Starnd: + Coordinate: Start Site(bp): 167826922 End Site(bp): 167972023 External Links: ENSG00000130396

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand WDR36 chr5 111091716 111130502 + AGO3 chr1 35930718 36072500 + TXNRD1 chr12 104215779 104350307 + TOMM34 chr20 44942130 44960397 - NFE2L1 chr17 48048329 48061545 + DDX5 chr17 64498254 64508199 - TMEM243 chr7 87196160 87220587 - PABPC3 chr13 25095868 25099254 + DHPS chr19 12675717 12681880 - CALU chr7 128739292 128773400 + NKTR chr3 42600655 42648735 + SON chr21 33543038 33577481 + MT-CO3 chrMT 9207 9990 + UVSSA chr4 1347208 1395989 + MYB chr6 135181308 135219173 + HOXB7 chr17 48607232 48633572 - ZNF395 chr8 28345590 28402701 - SREBF2 chr22 41833079 41907307 + KHSRP chr19 6413348 6424794 - RTEL1-TNFRSF6B chr20 63659300 63698684 + PANK3 chr5 168548495 168579368 - FDFT1 chr8 11795573 11839304 + TUBA1A chr12 49184795 49189080 - RINL chr19 38867830 38878275 - PPP1CA chr11 67398183 67421183 - SMC1A chrX 53374149 53422728 - ACTG1 chr17 81509971 81523847 - NIPSNAP1 chr22 29554808 29581327 - CYTH2 chr19 48469208 48482314 + ARHGDIB chr12 14942031 14961728 - miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-652-3p chrX 110055389 110055409 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC011498.1 chr19 4457962 4471493 - AC067930.4 chr8 143573490 143577397 + AD000090.1 chr19 35557956 35581954 + AL162586.1 chr9 127816066 127822520 + AP005263.1 chr18 9102736 9254346 + LINC00205 chr21 45288050 45297806 + LINC01578 chr15 92819540 92899701 + MALAT1 chr11 65497688 65506516 + NEAT1 chr11 65422774 65445540 + XIST chrX 73820649 73852723 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.